- Scientific and Technical Authority : Laetitia Andrique
VoxCell
You want to :
- Establish a 3D cell culture project
- Mimic the tumour complexity
- Proceed to drug screening on organoids
- Investigate the role of mechanics in a cell population organised in a 3D fashion
VoxCell Scientific Offer
The VoxCell interdisciplinary facility combines a Microfluidics technique with Biology to generate organoids and spheroids, or more generally 3D cell mono- or co-cultures.
Help for the design of your project
Cell encapsulation (in capsules or tubes)
Sample preparation
Quality control
Provision of small equipment for the analysis
Help and training for the manipulation of the spheroids/3D objects
Prices : on demand
THE CELLULAR CAPSULES TECHNOLOGY
The ‘Cellular Capsule Technology’ working principle starts with co-extruding a cell suspension and a polymer solution. By contacting a calcium bath, the polymer solution undergoes gelation resulting in cell-laden spherical and hollow capsules . The capsule is permeable to nutrients and favours the 3D assembly and self-organisation of the tissue or tumour microenvironment. Capsules are produced in a high throughput format (up to hundreds of thousands per encapsulation).
ADVANTAGES OF THIS TECHNOLOGY
1. Cell self-organization
- In capsules : ex: HEK 293T tumor spheroids
2. High Throughput
- Around 5000 capsules/second
- 1 to 2 meters of tubes in 10 minutes
3. Drug testing
4. Mechanical forces
equipements
- Culture room
- Encapsulation set-up
- 3D printers
- Analyse equipment
- Pump for perfusing 3D objects directly into an incubator
- Incubascope: high-throughput 3D object imaging system, placed in a dedicated incubator.
(https://pubmed.ncbi.nlm.nih.gov/35154792/)
Contact
Scientific Support
- pierre.nassoy@u-bordeaux.fr
- +33 5.57.01.72.09
- gaelle.recher@institutoptique.fr
- +33 5.57.01.72.69
Scientific & Technical Authority
- laetitia.andrique@u-bordeaux.fr
- +33 6.63.21.33.50
Localisation
TBMCORE | INSERM US 005 – CNRS UAR 3427
Université de Bordeaux
Bâtiment BBS
2 rue Hoffmann Martinot | 33076 BORDEAUX
